Pregnancy
It is one of the triggers for Graves disease in women. The major changes in hormones during pregnancy can make a woman prone to Graves disease, particularly if she has a positive family history. This is also a reason why women are more prone to Graves disease than men. Women who have recently given birth to a baby (post-partum period) are more prone to Graves disease.
Auto-immune diseases
Previous presence of other auto-immune diseases like Systemic Lupus Erythematosus, Rheumatoid Arthritis, Vitiligo, etc. might trigger Graves disease.
Frequent viral infections
People who are prone to frequent viral infections can also get Graves disease more as compared to others who do not get viral infections frequently.
Age
The chances of getting Graves disease increases with age.
Inflammation in eyes
Inflammation in the eyes, particularly in the muscles, along with increased proliferation of extra-ocular muscles, is associated with Graves' ophthalmopathy. It happens due to the action of thyroid-stimulating antibodies and the cytokines stimulated in response to it. The growth of retro-orbital connective tissue and fat tissues increases, and excess hydrophilic glycosaminoglycans (GAG) synthesis occurs. GAGs cause retro-orbital muscle swelling by trapping water in it, and ultimately, all of these changes are responsible for periorbital oedema and protrusion of eyeballs called Graves ophthalmopathy. This can lead to permanent muscle fibrosis if left untreated.
Conclusion
Graves disease is a medical condition that affects the thyroid, eyes, and skin, but it can also have systemic effects on other organs such as the heart, bones, and muscles. Recognizing the causes of Graves disease and managing this condition early is crucial. Fortunately, diagnosing Graves disease is straightforward through a patient's medical history and physical examination. Blood tests can determine if hyperthyroidism is present. By intervening promptly using health insurance with medical treatment, symptoms can be effectively controlled and thyroid hormone secretion can be reduced.
The above blog aims to provide general information about health and related topics. Any information provided in this blog, website or in any linked materials is not intended and should not be considered, or used as a substitute for any medical advice, diagnosis or treatment. It is important that you contact your Doctor before starting a new medicine or health regime.