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Causes of Muscular Sclerosis Disease

Delve into the enigma of Muscular Sclerosis, where genetics, age, infections, and environment converge. Learn about risk factors and proactive healthcare measures.

  • 15 Jan 2024
  • 3 min read

Muscular sclerosis (MS) causes decreased nerve function with initial inflammation of the protective myelin nerve. It is an autoimmune disease that affects the brain and spinal cord (central nervous system). In MS, the immune system attacks the myelin sheath and interrupts nerve signals from your brain to other parts. What causes muscular sclerosis in some people and not others is not clear, but scientists say that a combination of genetics and environmental factors appears to be responsible. 

What are the Causes of Muscular Sclerosis Disease?

Factors that may trigger MS include:

  • Age: The studies say that MS can occur at any age but more cases are mainly reported around 20 and 40 years of age. 
  • Sex: More cases of MS are reported in women i.e. 2 to 3 times as likely as men 
  • Family history: The cases of MS are linked with family history if any of the parents or siblings have had MS in the past.
  • Certain infections: The studies have reported cases of MS linked with a variety of viruses, including Epstein-Barr, the virus that causes infectious mononucleosis.
  • Race and Ethnicity: White people are more likely to get this disease as compared to people of Asian, African or Native American descent have the lowest risk. 
  • Climate: The cases of MS are far more common in countries with temperate climates, including Canada, the northern United States, and New Zealand, southeastern Australia Europe  etc. where temperature is either extremely cold or too hot.
  • Vitamin D: People with low levels of vitamin D and less exposure to sunlight are at greater risk of developing MD disease.
  • Your genes: A gene on chromosome 6p21 has been studied to be associated with multiple sclerosis. People with this gene are at greater risk of developing MS.

Also read:


Though the exact muscular sclerosis causes are not known, various risk factors like age, race, obesity, smoking, and family history of MS (genetics) can increase the likelihood of getting this disease. Talk to your healthcare provider to treat this condition to reduce and slow down disease progression.

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