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Causes of Small Intestine Cancer

Dive into the complexities of small intestine cancer and the various factors that may lead to its development.

  • 16 Oct 2023
  • 3 min read

A vital component of the digestive system, the small intestine performs a variety of functions, including producing hormones for digesting and housing immune cells that guard against mouth infections. Despite being uncommon, small intestinal cancer requires early detection and thorough management for improved patient outcomes. In order to properly handle this relatively uncommon malignancy and give people impacted the best care possible, it is imperative to know the exact cause of small intestine cancer. Read on to know more about the causes and risk factors of this condition.


How is Small Intestine Cancer Caused?

Let us explore how small bowel cancer develops and the elements that influence it in order to have a greater understanding of the causes of small intestine cancer:

  1. Genetic Alterations:
  • The root cause of small bowel cancer is genetic abnormalities.
  • The cells are forced to grow quickly as a result of these genetic alterations, eluding the normal cell cycle that would normally cause them to die.
  • This uncontrolled growth of cells plays a crucial role in the development of tumours and the spread of small bowel cancer, adding to its difficult and complex nature.
  1. Uncontrolled Growth:
  • Cancerous cells persist and multiply, whereas healthy cells normally experience programmed cell death.
  • A tumour could develop as a result of this unregulated proliferation's excessive cell accumulation.
  • Small bowel cancer is known for its rapid, uncontrolled cell development, which adds to the disease's difficult-to-treat and potentially invasive nature.
  1. Invasion and Spread:
  • The small intestine's healthy tissue may eventually become invaded with such unusual cells over time.
  • Additionally, they could separate from the primary tumour and spread via the lymphatic or circulatory systems to different parts of the body.

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Risk factors

The risk factors for developing small intestine cancer include -

  • Genetic factors like Lynch syndrome, FAP, and Peutz-Jeghers syndrome.
  • Bowel diseases like Crohn's, inflammatory bowel disease, and celiac disease.
  • Weakened immune systems.
  • Dietary habits, including alcohol and specific food choices.


Despite being uncommon, small intestine cancer is a complex malignancy that is primarily brought on by genetic anomalies that result in aberrant cell development and can be one of the main causes of small intestine cancer. These genetic changes cause the cell's regular instructions to be disrupted, causing the cell to grow uncontrollably and avoid planned cell death. By understanding all of the potential causes and symptoms of small intestine cancer, one can stay vigilant towards efforts for prevention--which is essential for keeping yourself healthy in the long run. Also, ensure that you have a health insurance plan in place to safeguard yourself against any financial stress.

Disclaimer: the above blog aims to provide general information about health and related topics. Any information provided in this blog, website or in any linked materials is not intended and should not be considered, or used as a substitute for any medical advice, diagnosis or treatment. It is important that you contact your doctor before starting a new medicine or health regime.

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