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Causes of Smallpox Disease

Smallpox is caused by the variola virus, part of the orthopoxvirus family, and primarily spread through person-to-person contact. The virus’s high contagiousness and lack of natural immunity contributed to its devastating impact. Vaccines have effectively controlled the disease, but vigilance remains crucial to prevent future outbreaks.

  • 09 Apr 2025
  • 3 min read
  • 7 views

Smallpox, a severe disease stemming from the variola virus was a significant illness, resulting in the loss of millions of lives, before its eradication. In this article, we'll explore the intricacies of smallpox, a historical adversary that plagued humanity. We’ll uncover the factors contributing to the onset of smallpox and understand why it once posed a serious threat.

What are the Causes of Smallpox?

Smallpox is caused by the following:

● Variola Virus

Small pox is caused by the variola virus. This virus, part of the orthopoxvirus family caused severe symptoms like high fever, malaise and severe aches. There were two main types – Variola Major and Variola Minor. While both were dangerous, Variola Major was the more serious of the two, causing severe cases and more fatalities.

  • Other Orthopoxvirus viruses

Humans are the only recorded carriers of the variola virus. Other Orthopoxvirus viruses were typically transmitted to humans from animals that were infected.

● Human Transmission

The primary mode of transmission was person-to-person, making it highly contagious. Sneezes, coughs, or even simple contact could turn someone into a carrier.

● Lack of Natural Immunity

This virus took advantage of the lack of natural immunity of people. A weakened immune system meant heightened consequences in battling this illness.

Conclusion

If you were pondering the question “Smallpox is caused by which virus?”, we hope this has helped shed light on the matter. Vaccines have been an effective tool in controlling the spread of smallpox, but vigilance needs to be maintained to ensure cases remain as rare as possible. If you know someone who may have contracted smallpox or has come into contact with its vesicles, report it to the local health authority immediately. Health insurance can provide financial support for vaccination and medical care, ensuring timely intervention and protection.

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