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Common Symptoms of Lupus Anticoagulant

Symptoms of Lupus Anticoagulants often present as blood clots in various parts of the body. Learn how identifying these signs can help prevent serious complications like strokes and miscarriages.

  • 09 Apr 2025
  • 3 min read
  • 9 views

Lupus anticoagulants, or LAs, are a unique type of antibody produced by the immune system. Unlike regular antibodies that protect the body from foreign substances, LAs target phospholipids found in cell membranes.

This condition is linked to antiphospholipid syndrome, an immune system disorder. A simple blood test can identify the presence of LAs.

Contrary to their name, LAs actually increase the risk of blood clotting rather than causing bleeding. LAs are often associated with systemic lupus erythematosus (SLE). But it is possible to have these antibodies without having lupus.

In this blog, we will explore the symptoms of lupus anticoagulants in detail.

Symptoms of Lupus Anticoagulant

The exact cause of LAs is not known, but factors like infections, medications, and autoimmune conditions may contribute to their development.

LAs are commonly found in people with other autoimmune conditions, particularly systemic lupus erythematosus (SLE). They can also occur in individuals with infections like HIV, hepatitis, and malaria, and those taking certain medications such as procainamide and chlorpromazine.

Evidence suggests that LAs are more prevalent with age and are relatively more common in females.

Some people with LAs may not experience any signs of lupus anticoagulant. For others, Lupus Anticoagulant is closely associated with thrombosis. Thrombosis refers to the blockage of blood vessels by clots. These clots can pose a life-threatening risk if not treated promptly.

Other potential complications include:

  • Stroke
  • Transient Ischemic Stroke (mini-stroke)
  • Acquired Thrombophilia (increased tendency for blood clotting)
  • Pregnancy Loss

Symptoms of Lupus Anticoagulant (LA) can vary depending on where the blood clot forms.

Let us understand these signs of lupus anticoagulant in detail:

  1. Blood Clot in the Heart or Lung Area:

    • Breathing Difficulty
    • Chest Pain
    • Dizziness
    • Fatigue
    • Heavy Sweating
  2. Blood Clot in an Arm or Leg:

    • Numbness in the Leg or Arm
    • Pain
    • Swelling
    • Discolouration or Redness
  3. Blood Clot in the Kidneys or Stomach:

    • Nausea
    • Bloody Stool
    • Diarrhoea
    • Stomach Pain
    • Thigh Pain
    • Fever

It is essential to remember that LAs can exist without the presence of lupus. Consequently, early detection and diagnosis is critical.  Individuals should promptly contact a doctor if they experience signs of lupus anticoagulant symptoms of a blood clot, such as

  • shortness of breath
  • arms or legs numbness/pain
  • paler-than-usual skin in the arms or legs
  • swelling or redness in the leg
  • repeated miscarriages

If you experience any of these symptoms of lupus anticoagulant or suspect a blood clot, make sure you seek immediate medical attention to ensure timely and appropriate treatment. There is no definite treatment to eradicate antiphospholipid syndrome, however, with treatment, the possibility of blood clotting can be slowed and managed. In such cases, having health insurance online can provide financial support for medical expenses and treatments.


Disclaimer: The information provided in this blog is for educational and informational purposes only. It is not intended as a substitute for professional advice, diagnosis, or treatment. Please consult your general physician or another certified medical professional for any questions regarding a medical condition. Relying on any information provided in this blog is solely at your own risk, and ICICI Lombard is not responsible for any effects or consequences resulting from the use of the information shared.

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