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Treatment for Syphilis Infection

Syphilis treatment involves antibiotics such as Benzathine penicillin G, with alternative options for penicillin-allergic individuals.

  • 05 Mar 2024
  • 2 min read

Syphilis, a sexually transmitted infection caused by the bacteria called Treponema pallidum, requires effective treatment to prevent the disease from progressing and causing complications. It is crucial to have an understanding of the syphilis treatment protocols, monitoring procedures, partner notification and preventive measures in order to manage infections successfully.


What are The Treatment of Syphilis Infection?


Let’s look at the syphilis treatment approaches in various stages of Syphilis Infection;


Early stage

During the early stages of syphilis (primary, secondary or early latent), it is recommended to receive a single injection of a long-acting antibiotic called Benzathine penicillin G for a complete cure.


Late latent Syphilis

For latent syphilis or when the duration of latent syphilis is unknown, the Centers for Disease Control and Prevention (CDC) suggests undergoing three doses of Benzathine penicillin G at weekly intervals for effective treatment.


Alternative antibiotics

In cases where individuals are allergic to penicillin, alternative antibiotics like doxycycline or tetracycline may be prescribed.


Monitoring and Follow-up

Patients being treated for syphilis should undergo regular follow-up evaluations to monitor their response to treatment and address any complications that may arise.


Partner Testing

It is extremely important for individuals diagnosed with syphilis to inform their partners about their diagnosis. They should encourage their partners to undergo testing.


Pregnant women

Pregnant women who have syphilis can be treated with penicillin, which effectively prevents transmission to the baby and reduces the risk of congenital syphilis. 


To avoid getting infected, individuals should take precautions such as consistently and correctly using condoms after syphilis therapy.




When syphilis is detected early and treated appropriately with antibiotics, it can be cured. Health insurance plan plays a key role in ensuring that individuals receive effective treatment for syphilis.


Disclaimer: The information provided in this blog is for educational and informational purposes only. It is not intended as a substitute for professional advice, diagnosis, or treatment. Please consult your general physician or another certified medical professional for any questions regarding a medical condition. Relying on any information provided in this blog is solely at your own risk, and ICICI Lombard is not responsible for any effects or consequences resulting from the use of the information shared.



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