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Treatment of Nipah Virus: Current Approaches and Challenges

With no approved cure for Nipah virus, treatment focuses on managing symptoms through hydration, pain medications, and anti-nausea drugs. Severe cases require hospitalization for respiratory support, fluid management, and seizure control. Research continues on experimental treatments including monoclonal antibodies (m102.4), antiviral drugs (remdesivir, ribavirin), and potential vaccines.

  • 29 Apr 2025
  • 3 min read
  • 1 views

Nipah virus (NiV) is a deadly zoonotic virus which is a severe threat to both humans and animals. The virus spreads mainly through fruit bats but can also be transmitted through pigs and other animals. It is highly contagious and causes severe respiratory illness and encephalitis in humans.

 

Nipah Virus Treatment: Supportive Care

Since there is no approved cure for Nipah virus, treatment focuses on managing symptoms. Here are a few ways to manage the symptoms:  

  • Hydration, proper nutrition and rest
  • Taking acetaminophen or ibuprofen, after consulting with a doctor
  • Using medications to control nausea or vomiting.
  • Using inhalers or nebulizers to improve breathing difficulties.
  • Taking antiseizure medications, when prescribed, if one experiences a seizure episode.

In severe cases, hospitalisation becomes necessary to receive:

  • Respiratory care: Oxygen therapy or ventilation
  • Fluid and electrolyte management: To prevent dehydration and maintain organ function
  • Seizure and fever control: Medications like antipyretics and anticonvulsants help manage symptoms under supervised care

 

Nipah Virus Medicine: Experimental Treatments and Research

Since there is no cure, researchers are actively exploring antiviral drugs to combat the Nipah virus. Some promising approaches include:

  • Monoclonal antibodies: Experimental antibodies, such as m102.4, have shown potential in animal studies.
  • Antiviral drugs: Remdesivir and ribavirin have been tested, but their effectiveness in humans remains unclear.
  • Vaccines: While no vaccine is currently available for public use, multiple research studies are being conducted to make one.

 

Conclusion

Since treatment options are limited, prevention is crucial. However, in severe cases, hospitalisation could become necessary. So, get a health insurance policy that covers your treatment and medical expenses during such emergencies.


Disclaimer: The information provided in this blog is for educational and informational purposes only. It is not intended as a substitute for professional advice, diagnosis, or treatment. Please consult your general physician or another certified medical professional for any questions regarding a medical condition. Relying on any information provided in this blog is solely at your own risk, and ICICI Lombard is not responsible for any effects or consequences resulting from the use of the information shared.

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