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What is the Treatment for Endometrial Cancer?

Explore the various treatments available for endometrial cancer, including surgery, radiation, chemotherapy, targeted therapy, and immunotherapy.

  • 09 Feb 2024
  • 3 min read

Our understanding of female reproductive health and how to treat diseases that affect those organs has come a long way. Yet, for many women, endometrial cancer remains a scary diagnosis, and its treatment is unclear. As one of the most common cancers of the female reproductive system, endometrial cancer arises from the lining of the uterus or endometrium. With advancements in medical research, oncologists now have several treatment options for endometrial cancer that can often cure it depending on how early it was detected and how far it has spread. In this article, we’ll explore those options for endometrial cancer treatment.

Treatment of Endometrial Cancer

Endometrial cancer treatment involves:

  • Surgery

Treatment for endometrial cancer usually involves a surgical procedure to remove the uterus, called a hysterectomy. The fallopian tubes and ovaries are removed when the cancer cell spreads, through a process called a salpingo-oophorectomy. 

  • Radiation Therapy

In this therapy, radiations using high-energy beams from sources such as X-rays and protons are targeted toward cancer cells causing them to die. Radiation therapy can be given to patients from a large machine placed outside the body (external beam radiation), or from little radioactive seeds and wires that can be placed inside your body where there is growth of cancer cells (brachytherapy). In the case of early-stage endometrial cancer that hasn’t spread to lymph nodes, radiation therapies are effective in treating the patient. However, in the case of advanced stages of cancer, radiation therapies are combined with chemotherapy or surgery to treat the patient.

  • Chemotherapy

This therapy uses drugs to kill cancer cells or stop them from multiplying, and is one of the most common options of endometrial cancer treatment. Some people receive one chemotherapy medicine, while in advanced stages, two or more medicines are combined in advanced endometrial cancer stages that have spread beyond the uterus or to treat cancer comeback cases. These drugs are given intravenously, which enter the bloodstream and travel through the body to kill cancer cells. Chemotherapy is generally done after surgery to lower the risk of reoccurrence. 

  • Targeted Therapy

Targeted therapy utilises drugs and other substances to target cancer cells by targeted therapy which is done using anti-angiogenic agents that block blood vessels and shrink them to enter the tumour. Such techniques are used after surgical procedures. The drug Everolimus is mostly used to perform targeted therapy, which stops the action of protein found in cancer cells to treat endometrial cancer in certain situations. 

  • Immunotherapy

This therapy enables the immune system to fight bladder cancer by restoring the body's natural defense mechanism and using immunotherapies like interferon alpha or interleukin-2 and standard immunotherapy drugs like pembrolizumab. These drugs are placed directly into the bladder through a catheter to perform intravesical therapy. This therapy is done to treat the advanced stage of endometrial cancer when standard treatments are not responding.

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Endometrial cancer is a serious concern that requires attention and treatment. With the right approach, it's very possible to beat this illness and lead a healthier life. Medical care can be pricey, however, which is why health insurance is so important. It provides coverage for treatments and offers peace of mind in knowing you are covered financially. Understanding your options around endometrial cancer treatment is essential; speak with your doctor about what’s best for you and your family. Take charge of your health today.

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