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What is the Treatment for Hyperplasia?

Discover the diverse landscape of hyperplasia treatment, focusing on progestin therapies designed for effective management. Gain insights into preventing or addressing hyperplasia with personalized and effective interventions.

  • 23 Jan 2024
  • 2 min read

Hyperplasia refers to the abnormal increase in the number of cells in an organ or tissue, causing it to enlarge. This can sometimes be an indication of abnormal or precancerous changes. This condition is called pathologic hyperplasia. The cell growth can also be normal, then it is called physiologic hyperplasia.

The condition is something that a lot of people come across but often aren't sure how to address. So, let's dive into the treatments available for this hyperplasia and see how we can prevent or manage this condition effectively.

Treatment of Hyperplasia

Endometrial hyperplasia is most common in women aged between 50 and 60. The treatment for this primarily revolves around progestin therapy. It is a synthetic form of progesterone, a hormone that is typically low in individuals with this condition. Here's a breakdown of the various forms of progestin treatment:

Oral Progesterone Therapy:

It is important to follow the prescribed dosage and schedule whenever we take progesterone orally. This method can be convenient but requires consistency in taking the pill daily. It is effective in reversing hyperplasia in many cases and is often the first line of treatment. However, it is important to be aware of potential side effects like mood swings or weight gain.

Intrauterine Device (IUD) Containing Progesterone:

An IUD provides direct and localised hormone therapy, which often results in fewer systemic side effects compared to oral therapy. It is a long-term solution and it is usually effective for up to five years. It is particularly beneficial for women who are also seeking contraception. The IUD needs to be inserted and eventually removed by a healthcare professional and this requires a clinic visit.

Injection (Depo-Provera®):

The Depo-Provera® injection is usually given once every three months. This makes it a convenient option for those who prefer less frequent dosing. It is important to note that it might take some time for fertility to return to normal after stopping the injections. So, it is a significant consideration for those planning future pregnancies.

Vaginal Cream or Gel:

This localised treatment is often well-tolerated and can be a good choice for those who experience side effects with oral progesterone. The direct application allows for the absorption of progesterone right where it is needed, potentially reducing systemic side effects. It is an especially suitable option for postmenopausal women or those who may have contraindications to systemic therapy.

Each method of delivering progesterone has its specific advantages and considerations. Therefore, it is crucial to have a detailed discussion with a healthcare provider to understand the best treatment plan tailored to individual health needs and lifestyles.

Also read:


Dealing with hyperplasia is all about understanding our options and finding what works best for us. There are effective treatments available with the advancements in medical science. Taking health insurance will be of great help during our treatment period, considering it may go on for a long. Remember, staying informed and taking proactive steps during hyperplasia treatment is key to managing our health effectively.

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