Addison's disease is a rare condition characterised by a deficiency in hormone production by the adrenal glands. The main reason for this condition is damage to the adrenal glands, leading to reduced cortisol and aldosterone production levels. Let's understand the causes of Addison's disease.
What are the Causes of Addison's Disease?
Although uncommon, various factors are responsible for causing Addison's disease. One such cause is adrenalitis, whereby the body's immune system inadvertently attacks and damages the adrenal glands, mainly targeting the vital adrenal cortex. This gradual destruction of cortex cells hampers their ability to produce hormones such as cortisol and aldosterone.
Certain infections, including associated tuberculosis and viral or fungal infections, can damage the adrenals. Genetic factors also play a role, with some individuals having a predisposition to disorders that affect the adrenals. Tumours affecting the adrenal - glands whether benign - can disrupt normal adrenal function and lead to Addison's disease.
Furthermore, severe bleeding into the adrenal glands (known as adrenal haemorrhage) and prolonged use of specific medications such as those used for tuberculosis can contribute to insufficient functioning of the adrenals.
In some cases, Addison's disease aetiology remains unclear; this is referred to as idiopathic and suggests a complex interplay between genetic and environmental factors.
It is essential to comprehend the factors contributing to its onset to ensure timely diagnosis and effective treatment of Addison's disease.
Conclusion
If you suspect you have Addison's disease or are experiencing symptoms, including fatigue, weight loss, and low blood pressure, you must seek immediate medical assistance for proper diagnosis and treatment. Moreover, health insurance can cover the expense of hormone replacement therapy for Addison's disease without requiring any out-of-pocket payments.