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Causes of Spleen Cancer

Explore the origins and risk factors behind spleen cancer, shedding light on the causes that contribute to this rare but serious condition.

  • 16 Oct 2023
  • 3 min read

Are you concerned about the potential causes of spleen cancer? While this type of cancer is relatively rare, understanding the different risk factors associated with it can help you keep an eye out for any changes or symptoms that might indicate something more serious. In this blog post, we'll explore some of the common causes and risk factors behind spleen cancer. Knowing what you're up against will put your mind at ease and give you a starting point as far as early detection goes. Keep reading to learn more – your health could depend on it!


How is Spleen Cancer Caused?

In most cases, spleen cancer is diagnosed as a secondary cancer, so it is important to focus on the stage of primary cancer and prevent spreading it up to the spleen. So, what causes spleen cancer? The following reasons are usually found to be associated with occurrence of primary splenic malignancy:

  • Hypersplenism – It refers to an overactive spleen that can lead to quick removal of blood cells so that the person may have very little amount of blood cells.
  • Splenic rupture – The spleen surface breaks, and it represents a medical emergency. It might occur due to any accident or a forceful blow on the abdomen. Sometimes, an enlarged spleen may also cause splenic rupture. Timely medical intervention allows a person to survive splenic rupture but makes him/her prone to frequent spleen infections and cancer.
  • Presence of splenic abscesses – Splenic abscesses due to other reasons might be a reason behind primary spleen cancer. It is frequently found in patients with underlying disorders such as:
    • Trauma
    • Infections
    • Recent surgery
    • Emboli
    • Immunosuppression
    • Hematologic malignancy
  • Presence of non-Hodgkin lymphoma – Primary splenic malignancy is a type of non-Hodgkin lymphoma that affects the lymphatic system.
  • Risk factors – Like male gender, advanced age, family history of lymphoma, frequent infections, weak immunity, and chronic hepatitis c infection.

Also read:

Causes of secondary spleen cancer –

  • Presence of other cancers - Cancers like leukaemia, lymphoma, breast cancer, melanoma and lung cancer are known to spread to the spleen and cause secondary spleen cancer.


With early diagnosis, treatment of spleen cancer can be straightforward and successful. Surgical resection or splenectomy is often the go-to option, but there are other therapeutic choices available too. Remember, the key to effective cancer treatment lies in timely detection and intervention. Stay vigilant and listen to your body's warning signs. By understanding the causes of spleen cancer, you can even help prevent this condition. Also, ensure that you have a health insurance plan in place to safeguard yourself against any financial stress.

Disclaimer: the above blog aims to provide general information about health and related topics. Any information provided in this blog, website or in any linked materials is not intended and should not be considered, or used as a substitute for any medical advice, diagnosis or treatment. It is important that you contact your doctor before starting a new medicine or health regime.

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