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Causes of Multiple Sclerosis Disease

Multiple Sclerosis arises due to immune system attacks on the nervous system, influenced by genetics, infections, or environmental factors. Understanding these causes aids in early detection and personalized treatment strategies to slow progression.

  • 08 Apr 2025
  • 3 min read
  • 14 views

The human body often digs its own grave. When our body begins to attack our own healthy cells, we refer to this type of condition as an autoimmune disorder. Multiple sclerosis is one of them.

What are the causes of multiple sclerosis disease?

Multiple sclerosis is caused by an attack of the immune system on myelin that eventually disables the brain and spinal cord. Just like other autoimmune diseases, the exact causes of multiple sclerosis are unknown, but it is associated with both genetic and environmental factors.

  • Genetic risk factors include genes that encode an immune molecule called HLA-DR2, which identifies and binds to foreign molecules.
  • Infections due to exposure to the Epstein-Barr virus, which spreads primarily through saliva.
  • Hormonal changes, particularly in women, influence the risk and course of MS. Fluctuations in estrogen levels during certain stages such as pregnancy or menopause might affect disease activity in some women with MS.
  • Vitamin D deficiency, due to which the rates of multiple sclerosis are higher at the northern and southern poles compared to the equator, where there’s a lot more sunlight.
  • Lifestyle causes include smoking. Smokers suffer from brain shrinkage.

Conclusion

In order to prevent flare-ups of multiple sclerosis, it is crucial to maintain a healthy lifestyle. And when nothing works right, health insurance from ICICI Lombard is all we need to recover from tragedies.


Disclaimer: The information provided in this blog is for educational and informational purposes only. It is not intended as a substitute for professional advice, diagnosis, or treatment. Please consult your general physician or another certified medical professional for any questions regarding a medical condition. Relying on any information provided in this blog is solely at your own risk, and ICICI Lombard is not responsible for any effects or consequences resulting from the use of the information shared.

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