Abnormal cell growth in the gallbladder can cause gallbladder cancer. Gallbladder cancer is uncommon, and early detection can treat the condition successfully. Even so, cancer in the gallbladder is usually detected very late, given the absence of specific signs and symptoms. Some common symptoms of gallbladder cancer include pain or lumps in the abdominal area, jaundice, and nausea or vomiting. An accurate gallbladder cancer diagnosis is crucial for planning treatment either through medication or by surgery.
Diagnosis of gallbladder cancer
Based on the signs and symptoms, various tests and procedures are recommended for diagnosing gallbladder cancer and determining its stage.
- Blood tests: These include the bilirubin test, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transferase, and albumin to determine whether there is a problem with the liver or gallbladder. Tumour markers associated with gallbladder cancer (for example, CEA and CA 19–9) can also be detected in the blood.
- Imaging tests: Ultrasound, computerised tomography (CT scan), and magnetic resonance imaging (MRI) of the abdominal area can provide a clear picture of any abnormality with the gallbladder.
Determining the stage of the cancer plays a crucial role in deciding upon treatment options and prognosis. The stages of gallbladder cancer range from 0 to IV. Stage 0 is the initial stage when the cancer is confined to the gallbladder, while at a later stage, the cancer has spread to nearby organs. Diagnostic procedures recommended to stage gallbladder cancer include:
- Exploratory surgery: The doctor may recommend surgery to look for signs of gallbladder cancer metastasis to other organs. A tiny camera is inserted into the abdomen through a small incision, and surrounding organs are observed for signs of cancer invasion.
- Cholangiography: This procedure is used for the examination of the bile ducts. The imaging of the ducts is usually done either by MRI, endoscopy, or direct insertion of a needle from the skin into the abdomen. In this procedure, a dye is injected into the bile ducts, followed by an imaging scan using magnetic resonance cholangiography and endoscopic retrograde cholangiography. Any blockage in the bile ducts can also be detected using these tests.
- A series of scans are required for people diagnosed with gallbladder cancer to determine the extent of cancer metastasis. A scan is recommended based on individual circumstances. Standard imaging scans recommended for gallbladder cancer are CT scans and MRIs of the chest and abdomen.
Conclusion
Gallbladder cancer is a rare but deadly disease if detected late. Early diagnosis is important for successful treatment. Blood tests and imaging scans are recommended based on the symptoms. Ultrasound, MRI, and CT scans are conducted to look for gallbladder abnormalities. Once the disease is diagnosed, the staging of the disease is critical for considering treatment options. Further diagnostic tests recommended for gallbladder cancer diagnosis are exploratory surgery and cholangiography. A timely diagnosis is critical for successful treatment. A health insurance plan usually covers the cost of tests recommended for gallbladder cancer diagnosis. Therefore, health insurance can provide financial benefits and peace of mind.