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Complete guide to endometrial cancer causes

Endometrial cancer develops through various factors including hormonal imbalances genetic predisposition and lifestyle influences. Early detection significantly improves treatment outcomes.

  • 24 Feb 2025
  • 4 min read
  • 41 views

Endometrial cancer also known as uterine cancer is a cancer that starts from the endometrium, which is the inner lining of the uterus.

As per the national cancer institute (NCI), it is estimated that approximately 3 in every 100 women may face the possibility of receiving a uterine cancer diagnosis at some point in their lives.

Early detection and diagnosis increase the chances of recovery from endometrial cancer.

In this blog, we will try to look at the causes of endometrial cancer.

  1. Hormone levels: Female sex hormones estrogen and progesterone are responsible for the health of the endometrium. When these hormones cause a shift in estrogen levels then it tends to increase, then the risk of being diagnosed with endometrial cancer rises.
  2. Number of years of menstruation: Having your periods at the early age of 12 years old and then entering menopause at a later stage increases your chances of suffering from endometrial cancer.
  3. Pregnancy history: When you are not able to conceive specifically due to infertility issues then your chances of having endometrial cancer are even higher.
  4. Polycystic ovarian syndrome (PCOS): PCOS is a hormonal disorder where the estrogen levels are more, and progesterone levels are less in the body. This leads to hormonal imbalance making you more prone to develop endometrial cancer.
  5. Estrogen replacement therapy (ERT): ERT at times is used to alleviate symptoms associated with menopause. ERT uses only estrogen putting you at a heightened risk of developing endometrial cancer.
  6. Obesity: As per the data provided by the American cancer society (ACS) women with a BMI of 25 TO 29.9 are two times more likely to develop endometrial cancer in comparison to women with lower BMI.
  7. Diabetes: According to the American cancer society, women suffering from type 2 diabetes are two times more likely to suffer from endometrial cancer.
  8. History of cancer: If you have a family history of lynch syndrome, breast cancer, or ovarian cancer raises your risk of endometrial cancer. Furthermore, undergoing radiation therapy in the pelvic region elevates the risk of developing endometrial cancer.

We have tried to cover some of the major causes of endometrial cancer. However, the causes may differ from person to person and affect people differently. Having a comprehensive health insurance plan can help cover the costs of screenings, consultations, and treatments, ensuring timely and effective care while alleviating financial stress.

 


Disclaimer: The information provided in this blog is for educational and informational purposes only. It is not intended as a substitute for professional advice, diagnosis or treatment. Please consult a certified medical and/or nutrition professional for any questions. Relying on any information provided in this blog is solely at your own risk, and ICICI Lombard is not responsible for any effects or consequences resulting from the use of the information shared.

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