Systemic lupus erythematosus (SLE) is an autoimmune disease. It occurs when the body's immune system attacks healthy tissue, and can affect the skin, joints, kidneys, brain, and other organs. It can cause many symptoms, like joint pain, fatigue and skin rashes. While there is no cure for lupus, different treatments can help manage the symptoms. In this article, we will explore the different approaches to lupus treatment.
Treatment of Lupus
Lupus treatment options depend on the patient’s specific signs and symptoms. Treatment usually involves the use of prescribed medicines like:
- Non-steroidal anti-inflammatory drugs (NSAIDs)
Over-the-counter NSAIDs, such as ibuprofen and naproxen, may be used to treat mild pain and swelling in joints and muscles associated with lupus. These medicines have certain side effects, which may include stomach bleeding, kidney problems and an increased risk of heart problems.
Prednisone and other corticosteroid types may help reduce swelling, tenderness, and pain. These medicines in higher doses can calm the immune system, but at the same time, have certain side effects like weight gain, easy bruising and thinning bones.
Medicines that prevent or treat malaria also treat symptoms like joint pain and skin rashes. The two common anti-malarial drugs are hydroxychloroquine and chloroquine phosphate, which can help to stop lupus flares and may help people with lupus live longer.
BlyS-specific inhibitors are used to treat lupus by blocking the action of specific abnormal B cells in the body. The drug used to treat lupus symptoms is belimumab.
- Immunosuppressive agents/chemotherapy.
Immunosuppressants are medications that may be used to treat severe cases of lupus, as these suppressants hold back your immune system and stop the patient from being as active. Immunosuppressants such as azathioprine, and mycophenolate can help prevent tissue damage and inflammation.
Certain medicines like belimumab and rituximab can be administered intravenously in people living with lupus to reduce the symptoms. These medicines are only recommended when other medicines are not helping in treatment as these medicines have some side effects like nausea, depression, diarrhoea and infections.
People living with lupus are also at risk for blood clots that can further cause stroke and heart attack. Anticoagulants such as warfarin and heparin are prescribed to prevent your blood from clotting too easily.